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COMPLEMENT FACTOR D
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DeCS
Descriptor
English
:
Complement Factor D
Descriptor
Spanish
:
Factor D de Complemento
Descriptor
Portuguese
:
Fator do Complemento D
Synonyms
English
:
Adipsin
C3 Convertase Activator
C3PA Convertase
Factor D
Properdin Factor D
Tree Number:
D08.811.277.300.450
D08.811.277.656.300.760.200
D12.776.124.486.274.045.450
Definition
English
:
A
serum
protein which is important in the ALTERNATIVE
COMPLEMENT ACTIVATION
PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound
COMPLEMENT FACTOR B
to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE.
Indexing Annotation
English
:
see SCR for organism-specific terms
Pharmacological Action:
Immunologic Factors
History Note
English
:
1999 (1978)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
23520
Unique Identifier:
D011416
Occurrence in VHL
:
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